Doran, Shawn D : rechercher sur Z-Library

Campagne de collecte 15 septembre 2024 – 1 octobre 2024 C'est quoi, la collecte de fonds?

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Campagne de collecte 15 septembre 2024 – 1 octobre 2024

Z-Library est une des plus grandes bibliothèques en ligne dans le monde, avec le stockage de plus de 17,000,000 livres et plus de 84,837,000 articles. Nous encourageons l'accès libre de chacun à la littérature. Aujourd'hui (15 septembre 2024) nous faisons un appel de fonds à tous ceux qui veulent contribuer encore plus au soutien et au développement de notre projet.

Les téléchargements SANS LIMITE sont aussi (au cours de 31 jours après la date de don) disponibles pour TOUS les utilisateurs qui soient en mesure de soutenir le projet pendant la période de collecte de fonds jusqu'au 1 octobre 2024.

C'est quoi, la collecte de fonds?En savoir plus

Livres
Articles (29)
Les plus populaires
Liste
- Liste
- Tableau

1

Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality

Butler, Christopher R., Ogilvie, Kevin, Martinez-Alsina, Luis, Barreiro, Gabriela, Beck, Elizabeth M., Nolan, Charles E., Atchison, Kevin, Benvenuti, Eric, Buzon, Leanne, Doran, Shawn, Gonzales, Cathl

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 3.44 MB

english, 2017

2

[IEEE 2008 International Symposium on VLSI Technology, Systems, and Applications (VLSI-TSA) - Hsinchu, Taiwan (2008.04.21-2008.04.23)] 2008 International Symposium on VLSI Technology, Systems and Applications (VLSI-TSA) - P-Channel I-MOS Transistor featuring Silicon Nano-Wire with Multiple-Gates, Strained Si1-yCy I-region, in situ doped Si1-yCy Source, and Sub-5 mV/decade Subthreshold Swing

Toh, Eng-Huat, Wang, Grace Huiqi, Weeks, Doran, Zhu, Ming, Bauer, M., Spear, Jennifer, Chan, Lap, Thomas, Shawn G., Samudra, Ganesh, Yeo, Yee-Chia

Année:

2008

Langue:

english

Fichier:

PDF, 2.75 MB

english, 2008

3

(3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: Synthesis, in vitro, in vivo, and X-ray crystallographic characterization

Stephen W. Wright, Mark J. Ammirati, Kim M. Andrews, Anne M. Brodeur, Dennis E. Danley, Shawn D. Doran, Jay S. Lillquist, Shenping Liu, Lester D. McClure, R. Kirk McPherson, Thanh V. Olson, Stephen J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 216 KB

english, 2007

4

(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: A potent, selective, orally active dipeptidyl peptidase IV inhibitor

Mark J. Ammirati, Kim M. Andrews, David D. Boyer, Anne M. Brodeur, Dennis E. Danley, Shawn D. Doran, Bernard Hulin, Shenping Liu, R. Kirk McPherson, Stephen J. Orena, Janice C. Parker, Jana Polivkova,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 828 KB

english, 2009

5

Piperidinyl-2-phenethylamino inhibitors of DPP-IV for the treatment of Type 2 diabetes

John W. Benbow, Kim A. Andrews, Jiri Aubrecht, David Beebe, David Boyer, Shawn Doran, Michael Homiski, Yu Hui, Kirk McPherson, Janice C. Parker, Judith Treadway, Maria VanVolkenberg, William J. Zembro

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 648 KB

english, 2009

6

Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonists

Paul S. Humphries, John W. Benbow, Paul D. Bonin, David Boyer, Shawn D. Doran, Richard K. Frisbie, David W. Piotrowski, Gayatri Balan, Bruce M. Bechle, Edward L. Conn, Kenneth J. Dirico, Robert M. Oli

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 267 KB

english, 2009

7

Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2

Jeffrey W. Corbett, Kevin D. Freeman-Cook, Richard Elliott, Felix Vajdos, Francis Rajamohan, Darcy Kohls, Eric Marr, Hailong Zhang, Liang Tong, Meihua Tu, Sharad Murdande, Shawn D. Doran, Janet A. Hou

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 987 KB

english, 2010

8

1-((3S,4S)-4-Amino-1-(4-substituted-1,3,5-triazin-2-yl) pyrrolidin-3-yl)-5,5-difluoropiperidin-2-one inhibitors of DPP-4 for the treatment of type 2 diabetes

Kim M. Andrews, David A. Beebe, John W. Benbow, David A. Boyer, Shawn D. Doran, Yu Hui, Shenping Liu, R. Kirk McPherson, Constantin Neagu, Janice C. Parker, David W. Piotrowski, Steven R. Schneider, J

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2011

Langue:

english

Fichier:

PDF, 999 KB

english, 2011

9

Simulating the spatial dynamics of foot and mouth disease outbreaks in feral pigs and livestock in Queensland, Australia, using a susceptible-infected-recovered cellular automata model

Ruth J. Doran, Shawn W. Laffan

Journal:

Preventive Veterinary Medicine

Année:

2005

Langue:

english

Fichier:

PDF, 318 KB

english, 2005

10

Maximizing Lipophilic Efficiency: The Use of Free-Wilson Analysis in the Design of Inhibitors of Acetyl-CoA Carboxylase

Freeman-Cook, Kevin D., Amor, Paul, Bader, Scott, Buzon, Leanne M., Coffey, Steven B., Corbett, Jeffrey W., Dirico, Kenneth J., Doran, Shawn D., Elliott, Richard L., Esler, William

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 380 KB

english, 2012

11

Comparative analysis of the neurophysiological profile of group II metabotropic glutamate receptor activators and diazepam: Effects on hippocampal and cortical EEG patterns in rats

Chester J. Siok, Shawn M. Cogan, Lauren B. Shifflett, Angela C. Doran, Bernat Kocsis, Mihály Hajós

Journal:

Neuropharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2012

12

Endogenous nitric oxide in expired air: Effects of acute exercise in humans

John Anthony Bauer, Jeffrey A. Wald, Shawn Doran, David Soda

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 397 KB

english, 1994

13

Discovery of CP-866,087, a mu opioid receptor antagonist for the treatment of alcohol abuse and dependence

McHardy, Stanton F., Heck, Steven D., Guediche, Sara, Kalman, Monica, Allen, Martin P., Tu, Meihua, Bryce, Dianne K., Schmidt, Anne W., Vanase-Frawley, Michelle, Callegari, Ernesto, Doran, Shawn, Grah

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 151 KB

english, 2011

14

cis -2,5-Dicyanopyrrolidine Inhibitors of Dipeptidyl Peptidase IV: Synthesis and in Vitro, in Vivo, and X-ray Crystallographic Characterization

Wright, Stephen W., Ammirati, Mark J., Andrews, Kim M., Brodeur, Anne M., Danley, Dennis E., Doran, Shawn D., Lillquist, Jay S., McClure, Lester D., McPherson, R. Kirk, Orena, Stephen J., Parker, Jani

Journal:

Journal of Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 225 KB

english, 2006

15

Disconnect between brain and CSF drug exposure and beta-amyloid levels following BACE inhibition

Gonzales, Cathleen, Ambroise, Claude, Robshaw, Ashley, Chang, Cheng, Hajos-Korcsok, Eva, Nolan, Charles, Atchison, Kevin, Doran, Shawn, Brodney, Michael, O'Neill, Brian, Riddell, David

Journal:

Alzheimer's & Dementia

Année:

2013

Langue:

english

Fichier:

PDF, 81 KB

english, 2013

16

[ECS 214th ECS Meeting - Honolulu, HI (October 12 - October 17, 2008)] ECS Transactions - SiCP Selective Epitaxial Growth in Recessed Source/Drain Regions yielding to Drive Current Enhancement in n-channel MOSFET

Bauer, Matthias, Machkaoutsan, Vladimir, Zhang, Yangting, Weeks, Doran, Spear, Jennifer, Thomas, Shawn, Verheyen, Peter, Kerner, C., Clemente, F., Bender, Hugo, Shamiryan, D., Loo, Roger, Hikavyy, A.,

Année:

2008

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2008

17

[IEEE 2007 International Semiconductor Device Research Symposium - College Park, MD, USA (2007.12.12-2007.12.14)] 2007 International Semiconductor Device Research Symposium - Strained Si n-FET featuring compliant SiGe Stress Transfer Layer (STL) and Si0.98C0.02 source/drain stressors for performance enhancement

Grace Huiqi Wanga,, Eng-Huat Toh,, Weeks, Doran, Landin, Trevan, Spear, Jennifer, Chih Hang Tung,, Thomas, Shawn G., Ganesh Samudra,, Yee-Chia Yeo,

Année:

2007

Langue:

english

Fichier:

PDF, 229 KB

english, 2007

18

[IEEE 2008 International Symposium on VLSI Technology, Systems, and Applications (VLSI-TSA) - Hsinchu, Taiwan (2008.04.21-2008.04.23)] 2008 International Symposium on VLSI Technology, Systems and Applications (VLSI-TSA) - Strained FinFETs with In-situ Doped Si1-yCy Source and Drain Stressors: Performance Boost with Lateral Stressor Encroachment and High Substitutional Carbon Content

Liow, Tsung-Yang, Tan, Kian-Ming, Weeks, Doran, Lee, Rinus T. P., Zhu, Ming, Hoe, Keat-Mun, Tung, Chih-Hang, Bauer, M., Spear, Jennifer, Thomas, Shawn G., Samudra, Ganesh S., Balasubramanian, N., Yeo,

Année:

2008

Langue:

english

Fichier:

PDF, 188 KB

english, 2008

19

Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes

Griffith, David A., Kung, Daniel W., Esler, William P., Amor, Paul A., Bagley, Scott W., Beysen, Carine, Carvajal-Gonzalez, Santos, Doran, Shawn D., Limberakis, Chris, Mathiowetz, Alan M., McPherson,

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2014

20

[IEEE 2007 International Semiconductor Device Research Symposium - College Park, MD, USA (2007.12.12-2007.12.14)] 2007 International Semiconductor Device Research Symposium - Source/drain-extension-last process for incorporating in situ doped lattice-mismatched extension stressor for enhanced performance in SOI N-FET

Hoong-Shing Wong,, Kah-Wee Ang,, Lap Chan,, Keat-Mun Hoe,, Chih-Hang Tung,, Balasubramaniam, N., Weeks, Doran, Landin, Trevan, Spear, Jennifer, Thomas, Shawn G., Samudra, Ganesh, Yee-Chia Yeo,

Année:

2007

Langue:

english

Fichier:

PDF, 334 KB

english, 2007

21

[ECS 213th ECS Meeting - Phoenix, AZ (May 18 - May 23, 2008)] ECS Transactions - Throughput Considerations for In-Situ Doped Embedded Silicon Carbon Stressor Selectively Grown into Recessed Source Drain Areas of NMOS Devices

Bauer, Matthias, Zhang, Yangting, Weeks, Doran, Brabant, Paul, Italiano, Joe, Machkaoutsan, Vladimir, Thomas, Shawn G.

Année:

2008

Langue:

english

Fichier:

PDF, 942 KB

english, 2008

22

Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase

Kung, Daniel W., Griffith, David A., Esler, William P., Vajdos, Felix F., Mathiowetz, Alan M., Doran, Shawn D., Amor, Paul A., Bagley, Scott W., Banks, Tereece, Cabral, Shawn, Ford, Kristen, Garcia-Ir

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2015

23

INHIBITION OF BACE2 AFFECTS MELANOSOME ULTRASTRUCTURE AND CAUSES OF HYPOPIGMENTATION

Nolan, Charles E., Karanian, David, Chang, Cheng, Lanyon, Lorraine F., Houle, Christopher, Pandher, Karamjeet, Boucher, Germaine, Hales, Katherine, Gonzales, Cathleen, Ambroise, Claude, Doran, Shawn,

Journal:

Alzheimer's & Dementia

Année:

2016

Langue:

english

Fichier:

PDF, 78 KB

english, 2016

24

[ECS 211th ECS Meeting - Chicago, Illinois (May 6-May 10, 2007)] ECS Transactions - Defect Free Embedded Silicon Carbon Stressor Selectively Grown into Recessed Source Drain Areas of NMOS Devices

Bauer, Matthias, Zhang, Yangting, Weeks, Doran, Machkaoutsan, Vladimir, Thomas, Shawn

Année:

2007

Langue:

english

Fichier:

PDF, 656 KB

english, 2007

25

The Discovery of a Novel Phosphodiesterase (PDE) 4B-preferring Radioligand for Positron Emission Tomography (PET) Imaging

Zhang, Lei, Chen, Laigao, Beck, Elizabeth M., Chappie, Thomas A., Coelho, Richard V, Doran, Shawn D, Fan, Kuo-Hsien, Humphrey, John M., Hughes, Zoe, Kuszpit, Kyle, Lachapelle, Erik A, Lazzaro, John T.

Journal:

Journal of Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2017

26

Late-Stage Microsomal Oxidation Reduces Drug-Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189

Stepan, Antonia F., Tran, Tuan P., Helal, Christopher J., Brown, Maria S, Chang, Cheng, O'Connor, Rebecca E, De Vivo, Michael, Doran, Shawn D, Fisher, Ethan L., Jenkinson, Stephen, Karanian, David, Ko

Journal:

ACS Medicinal Chemistry Letters

Année:

2018

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2018

27

Identification of a novel positron emission tomography (PET) ligand for imaging β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) in brain

Zhang, Lei, Chen, Laigao, Dutra, Jason K, Beck, Elizabeth M., Nag, Sangram, Takano, Akihiro, Amini, Nahid, Arakawa, Ryosuke, Brodney, Michael A., Buzon, Leanne M, Doran, Shawn D, Lanyon, Lorraine F, M

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2018

28

Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation

O'Neill, Brian T., Beck, Elizabeth M., Butler, Christopher R., Nolan, Charles E., Gonzales, Cathleen, Zhang, Lei, Doran, Shawn D, Lapham, Kimberly, Buzon, Leanne M, Dutra, Jason K, Barreiro, Gabriela,

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 2.70 MB

english, 2018

29

Quantitative Analysis of 18 F-PF-06684511, a Novel PET Radioligand for Selective β-secretase 1 Imaging, in Non-human Primate Brain

Takano, Akihiro, Chen, Laigao, Nag, Sangram, Brodney, Michael A, Arakawa, Ryosuke, Chang, Cheng, Amini, Nahid, Doran, Shawn D, Dutra, Jason K, McCarthy, Timothy J, Nolan, Charles E, O'Neill, Brian T.,

Journal:

Journal of Nuclear Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2018